Campus Moncloa
Campus of International Excellence
Biologically relevant heterocycles
Main research lines
- Neurodrugs
Objetives: Discovery of new neuroprotecting agents
Methodologies: Interference with prion and amiloid proteins. - Diversity-oriented synthesis in drug discovery
Objetives: Development of new synthetic methodologies for the exploration of chemical and biological space, with the aim pf generating bioactive molecules
Methodologies: Domino and multicomponent reactions. - Inhibitors of antitumor resistance
Objetives: Discovery of new inhibitors of the P-170 glycoprotein, which is responsible for antitumor drug resistance through the MDR (Multi Drug Resistance) mechanism. - New antitubercular agents
Objetives: Discovery of new compounds active against Mycobacterium tuberculosis. - New antitumour agents
Objetives: Discovery of new compounds with anticancer activity and methods for their characterization and quantitation - Fluorescent sensors
Objetives: Development of new compounds that allow the detection and quantitation of chemical species with diagnostic interest in biomedicine - Eco-compatible chemistry
Objetives: Development of sustainable chemical processes for the synthesis and analysis of bioactive molecules
Methodologies: Cromatografía eco-compatible. - New antiprotozoal agents
Objetives: Design, synthesis and evaluation of new drugs agains parasitic diseases caused by protozoa, including malaria and leishmaniosis
Top
Head:
José Carlos Menéndez Ramos
UCM reference: 920234
Keywords:
Diversity-oriented synthesis for drug discovery.
Neuroprotecting agents.
Antitumor agents.
Antitubercular agents.
Theranostics.
Drug nanocarriers.
News of the cluster
- Advances in models for early prediction of crises in chronic diseases
- International Mentor Program (IMP) USA-Europe
- First direct evidence for ultra-fast responses in human amygdala to fear
- Open call MIT-Spain - CEI Moncloa Seed Fund
- Videogames against malaria: learn through playing A Malaria "Candy Crush" to research new diagnostic tools involving citizen participation.