Campus Moncloa
Campus of International Excellence
Free Radicals and Aging
Main research lines
- Mitochondrial Free Radicals, Aging and Longevity
Objetives: To clarify the causal basic mechanisms of aging and longevity of the different animal species
Methodologies: dietary restriction. methionine dietary restriction. comparisons between different animal species. in vitro studies in functional isolated mitochondria. High perfomance liquid chromatography. Mass spectrometry. Clark electrode (polarography) respirometry in isolated mitochondria. Fluorometry. Western blot. Confocal and fluorescence microscopy. Gas chromatography. Amino acid analyses. Differential and gradient centrifugation. Eespectrofotometry.
Top
7
Head:
Gustavo Barja de Quiroga Losada
UCM reference: 910521
Keywords:
Mitochondria.
Free Radicals.
Aging.
Longevity.
ROS (Reactive Oxygen Species).
mitochondrial DNA.
Oxidative damage.
protein oxidation.
fatty acids.
caloric restriction.
methionine restriction.
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